Some items also reduce Isaac's own statistics such as Soy Milk, which greatly lowers his damage in favor of more tears), Empowerment (Gets significantly stronger and faster when certain conditions are fullfilled and he holds items such as Crown of Light or Whore of Babilon), Berserk Mode (With items such as Bloody Lust, Blind Rage and Berserk), Reactive Power Level (With items such as Bloody Lust and Cancer, Isaac can activate various effects upon being hurt), BFR (Can summon Mom's hands to drag enemies away with Emergency Contact), Animal Manipulation (Can control various critter familiar as well as friendly flies, locusts and spiders that attack the enemy), Summoning (Can summon various beings, such as flies, spiders, familiars with various items, Mom with things such as Emergency Contact or The High Priestess and Delirium with Delirious), Clairvoyance (Isaac can obtain a map of the floor by seeing the future with Crystal Ball, as stated by its item description), Void Manipulation, Power Absorption and Absorption (Can absorb items into Void, allowing for the use of any active item's effects repeatedly while consuming passive items and turning them into stats), Supernatural Luck and Probability Manipulation ( Lucky Foot increases his odds at gambling and makes all the pills he consumes beneficial and various trinkets or items such as Glyph of Balance alter the room drops), possibly minor Fate Manipulation ( Sacred Orb has similar effects, causing bad items to spawn less often, but its description, "destined to greatness", implies it being a fate manipulating ability), Duplication (Can duplicate his familiars with the Box of Friends, duplicate items with Diplopia or Crooked Penny and even duplicate enemies with Meat Cleaver, while making them smaller, weaker and slower), Creation (Can create coins with Wooden Nickel or items with Flip), Teleportation (Can teleport to other rooms with various items and cards, or teleport around mid-combat with Stitches), Forcefield Creation (Can create a temporary forcefield around himself with Book of Shadows or surround himself with a one-hit, regenerating holy shield with Holy Mantle), Blood Manipulation (Is capable of firing blood tears with various items, as well as leave a trail of harmful blood wherever he walks with items such as Anemic, fire a beam of blood with Brimstone or give life to a small army of Blood Clots with Sumptorium), Fragrance Manipulation ( Bean items each have a special fart effect), Energy Projection (Can fire energy beams with various items such as Shoop Da Whoop!), Acrobatics (Can perform quick sequences of horizontal jumps with How to Jump, and use them to avoid enemy attacks among other things), Flight (First four types. Some items as well as many cards can also temporarily increase his stats, such as the XI - Strength card which increases his power and health for the room, or Red Stew, which gives him a huge but slowly fading attack boost), Statistics Reduction (Capable of reducing the speed of the opponent with various items as well as halve their defenses for one minute with XI - Strength?. Capable of regrowing or reattaching his head after it is destroyed or removed by items such as The Intruder or Decap Attack), Statistics Amplification (Many if not most of Isaac's items permanently increase his statistics. ![]() Berserk! allows Isaac to survive wounds that would normally be lethal, although he will die once the berserk effect runs out), Resurrection (Can come back from the dead with various items), Regeneration (Mid. If Isaac picks up Isaac's Heart, Isaac will become invincible, but reliant on the heart's survival to live. Danmaku, Martial Arts (With Suplex!), Immortality (Varies among Type 2, 3, 4, 7 and 8.
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